@panyagua "Edinburgh's largest high-tech hub"?
I know that the University of Edinburgh's Information Services department is based in Argyle House, but I'm curious as to what else is there? (I'm vaguely aware that Amazon and Microsoft are in the old GPO, but I wasn't aware that there was any sort of Edinburgh silicon volcano as such…?)
(Oh, and my route suggestion would be: Shandwick Place, disregard the unnecessary-for-bikes one-way on Canning Street, and then, either: West Approach Road, Lothian Road (southbound), kerb-hop to Usher Hall plaza and onwards (there really should be a cycle access point there), or, probably less traumatic at peak times: Rutland Square, overbridge, unFestival Square (ditto cycle access point required on this side as well).
Actually, if Festival Square really wants to live up to its name, and be a place for people, there should be an additional crossing on the north side of the square (to mirror that near the Filmhouse), and Lothian Road should be swerved westwards in a gentle semicircle, to both slow the traffic and greatly expand the (probably more useful for festive purposes) plaza outside the Usher Hall in place of the mediocre "military parade ground" outside the Sheraton Hotel.)