It still doesn’t add up. MediumDave is saying we have vaccines for Hep A, polio, etc. (Pretty sure we do) And these are RNA viruses.
Bax says there are no successful RNA vaccines.
So which is it to be?
CityCyclingEdinburgh Forum » Debate!
Do we need a coronavirus thread?
(5710 posts)-
Posted 5 years ago #
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(That’ll be England)
Posted 5 years ago # -
@neddie
i'd suggest MediumDave is referring to standard protein-based vaccine delivery, as opposed to giving an instruction via rna for the body to create the protein itself
ergo, neither of us are wrong
Posted 5 years ago # -
tl;dr @bax is right about what I meant.
Longer - my apologies, my post was badly worded. Also - I don't have any expertise in this area, just a lay interest (don't we all these days?) and a baaad new scientist habit! I'd welcome corrections from anyone who actually knows what they are talking about.
Anyway, as I understand it:
SARS-CoV2 is an RNA virus. RNA viruses can be difficult to develop vaccines for, often because of fast mutation rates. Some RNA viruses don't have vaccines at all, but there are plenty that do have vaccines created by means such as attenuated live virus, inactivated virus and extracted viral proteins.
RNA vaccines are a newish vaccine development technique which is promising, but hasn't yet yielded a usable vaccine for anything. Some background here:
http://sitn.hms.harvard.edu/flash/2015/rna-vaccines-a-novel-technology-to-prevent-and-treat-disease/
Nice history of vaccine types in general:
https://www.niaid.nih.gov/research/vaccine-types
My point was that even if the RNA vaccine approach doesn't work, there are other approaches that may well yield a workable vaccine.
Finally, I turned up this nice article giving an overview of all the approaches and why they might or might not work for SARS-CoV2:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136867/
The section titled "The Current Pipeline for SARS-CoV-2 Vaccines" is probably most relevant to this discussion. I suspect things may have moved on in the month since the article was published.
Posted 5 years ago # -
What would poses someone to leave New Zealand to come to the UK during this pandemic?
https://www.bbc.co.uk/news/amp/uk-scotland-highlands-islands-52697289?__twitter_impression=true
Posted 5 years ago # -
A rather public break up with one's spouse?
Posted 5 years ago # -
the couple agreed "that we needed to give each other some space"
LOL.. well they certainly did that..
Posted 5 years ago # -
Skye about same as Auckland. Lot of Scientology in NG’s past. He says God certainly exists in the DC Universe.
AFP was your first statue in Edinburgh
Posted 5 years ago # -
"What would possess someone to leave New Zealand to come to the UK during this pandemic?"
Probably read right wing papers that were trumpeting about end of lockdown in England and assumed it applied here?
Why would he put it on social media though? Must have zero self-awareness about how his actions justify all these 'but it's me' types. Ian Blackford has publicly told him off - can't be unexpected if he had really been paying attention
He says it's his home and on voter's role. Pays UK taxes (with Sc tax code?)
Posted 5 years ago # -
Up to 20% of hospital patients in England got coronavirus while in for another illness
Some infections were passed on by hospital staff who were unaware they had Covid-19
https://www.theguardian.com/world/2020/may/17/hospital-patients-england-coronavirus-covid-19
Posted 5 years ago # -
ye olde covid19 vaccine status tracker
Posted 5 years ago # -
Initial Scottish lockdown easing plans released today. Seem to be much the same as England's, bar the timing (from 28th May) and more coheerent presentation.
Posted 5 years ago # -
At least the Scottish Government seem to be doing things in the right order - drafting plans and get their lines straight BEFORE announcing those plans. Whereas the UK Government now seem to favour a more freeform jazz approach to tackling public health emergencies - which probably means we are going to wait a very, very long time for this to end.
Posted 5 years ago # -
The motorbike group I'm in is made up mostly of people in England, and they've become quite tiresome, to the point I was minded to leave the group.
Ever since lock down started they've been jumping up and down like they had ants in their pants, because they couldn't ride their bikes. At first if someone went for a fly trip 'to the shops' involving two hundred miles of tarmac and green laning they got pelters from some of the group. Then it quietened down somewhat with people posting photos of past overlanding expeditions to places like Morocco.
Now they've got wind of lock down being adjusted. "We can ride our bikes!" "I've organised a route, come and join me!" "There's a cafe opened up we can go to!" "It's for my wellbeing and mental health!" Exercise? What exercise?
I would like to tell them that if they have plans to come north of the border they can [rule 2]. They seem to have forgotten, too, that sometimes motorbikes break down and have to be rescued. You'd better hope the driver of the flatbed has PPE to share out.
Posted 5 years ago # -
“
residents in one luxury apartment complex in Edinburgh appear to be taking more extreme measures to avoid contracting the coronavirus
“
Posted 5 years ago # -
Bah, obnoxious female roadie bellowed ‘pavement’ at me tonight as I tried to give people (more vulnerable than me) room on said pavement.
Posted 5 years ago # -
Some bad people on bikes. Plenty good ones though.
Posted 5 years ago # -
@SRD - encounters with turnips are especially tiresome at the moment. Does make me think though, assuming this wasn't a person having a very bad day, how it must be to live like that. Always angry and impatient - almost everyone you encounter taking an instant dislike to you. I would like to think that a low level frosty reception everywhere they go is payback for such behaviour, but in my experience these sorts of people have so little self awareness that they simply don't notice.
Posted 5 years ago # -
I almost gave a couple of roadies a bit of a telling off weekend before last. They both overtook me at the same time
As was lang whang i could see them drafting each other for some miles. The fitter one seemed to go steady whereas the one who was sweating buckets blew hot and cold. Up front/off the back etc
Eventually the fitter one continued west and the sweaty one peeled off to West Calder
They had not been out cycling together at all they had just become locked in a competition with each other.
Perspective is all.
I was once told to keep left by an obnoxious roadie (on meadows path) she meant get out of my way. Keep left I shouted after this roadie, I’m an anarcho-syndicalist - made me laugh and not bottle it up. The keep left roadie will not have remembered this at all. Just bashed on as they tend to be MGIF these obnoxious roadies. Also tend to be bagging strava segments which is no way to live.
Getting shouted at for doing a good turn is always the worst thing.
Posted 5 years ago # -
I’m thinking she was a medic heading home after a difficult shift. I was just heading to Scotmid to get some milk, after a family walk. It wasn’t a great place for me to be in the road, but we were basically in the door zone...
Incidentally we had earlier walked that path along the railway to Colinton from the Royal Ed. Had never done it before!
Posted 5 years ago # -
Slowing down is an option, there is no race
What path along a railway from Royal Ed to Colinton?
Posted 5 years ago # -
“What path along a railway from Royal Ed to Colinton?“
Mentioned many times on CCE.
Seldom found...
Posted 5 years ago # -
https://www.google.com/maps/@0,0,0a,13.1y/data=!3m4!1e1!3m2!1sQN-xrtO4fOlQv81S31Q9JA!2e0
Swing left
Posted 5 years ago # -
@chdot
That link takes me to route from auchengray to Wilsontown Ironworks which is a left swing for sure
Posted 5 years ago # -
Posted 5 years ago #
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@Iwrats thicket?
Posted 5 years ago # -
@gembo the one you say is muddy? Or maybe that was someone else. But had it in my head that it was you.
Posted 5 years ago # -
Now people in twitter are telling me “ You should be supporting the widening of pavements and cycle lanes if you’re going to walk in the road.”.
Wish I’d counted up all the hours I spent on Pop...
Posted 5 years ago # -
Oh dear, twitterati at it now too
IWRATS has a path descends myreside from Craighouse.
Posted 5 years ago #
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